Question 1

What is the best anti-thyroid regimen in a pregnant woman who has clinically significant hyperthyroidism?

Options :

A : Stop treatment and resume post-partum

B : Propylthiouracil

C : Methimazole

D : Propylthiouracil first trimester followed by methimazole for the remainder of pregnancy

E : Methimazole first trimester followed by propylthiouracil for the remainder of pregnancy

Answer: D

Question 2

Which of the following statements is true regarding Drug-receptor bonds?

Options :

A : Covalent bonds of drugs with receptors are strong and mostly reversible

B : Covalent bonding is much more common than electrostatic bonding in drug-receptor interactions

C : Electrostatic bonds are stronger than covalent bonds

D : Hydrophobic bonds are weak bonds and they are important in the interactions of highly water soluble drugs with the lipids of cell membranes

E : Bond formation of between the acetyl group of aspirin and cyclo-oxygenase enzyme is a covalent bond

Answer: A

Question 3

CJ is a 69-year-old male with a history of diabetes, hypertension and hypercholesterolemia. His fasting lipidprofile is TC 530 mg/dL; LDL-C 125; HDL-C 48 mg/dL; and TG 640 mg/dL. His A1c 8.1, calculate creatinineclearance is 65mls/hr, BP 135/80 mm Hg, HR 70 beats /min.His current medications include metformin 1000mg po bid, lisinopril 20mg daily, sitagliptin 50mg bid andatorvastatin 40mg daily.What is the best pharmacological agent to initiate on CJ?

Options :

A : Increase atorvastatin to 80mg

B : Niacin 500mg twice daily

C : Fenofibrate 162mg daily

D : Gemfibrozil 600mg twice daily

E : Fish oil 500mg twice daily

Answer: C

Question 4

A fasting blood glucose level greater than what value is an indicator of type 2 diabetes?

Options :

A : 5 mmol/L

B : 6 mmol/L

C : 7 mmol/L

D : 8 mmol/L

E : 9 mmol/L

Answer: C

Question 5

Which of the following medication can lower seizures threshold?

Options :

A : Bupropion

B : Tramadol

C : Clozapine

D : Thiothixene

E : All of the above can lower seizure threshold

Answer: A

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